Leonardo Jaimes, MD

All articles by Leonardo Jaimes, MD

• Vutrisiran associated with better functional capacity in ATTR-CM

  Vutrisiran appears to effectively conserve functional capacity and quality of life (QOL) in patients with ATTR-CM.

• Acoramidis decreases hospitalization rate in ATTR-CM

  A new study reports that treatment with acoramidis decreases the rate of all-cause mortality and cardiovascular hospitalization in patients with ATTR-CM.

• Study assesses innovative experimental therapies to treat ATTR-CM

  Gene silencing and antifibril therapy could stop disease progression and eliminate amyloid deposits in patients with ATTR-CM.

• Affordability is the major obstacle to ATTR-CM treatment, study says

  The barriers to treatment of ATTR-CM included lack of affordability, delayed diagnosis and underrepresented populations in clinical trials.

• Case of ATTR-CM had symptoms usually associated with other heart condition

  A case of transthyretin amyloid cardiomyopathy (ATTR-CM) presented with symptoms generally associated with a different heart condition.

• Index shows greater prognostic accuracy for mortality in patients with ATTR-CM

  The stroke volume index appears to have greater prognostic accuracy for mortality in ATTR-CM than traditional echocardiographic indexes.

• Evidence supports treatment of asymptomatic ATTR-CM

  Patients with asymptomatic ATTR-CM and high cardiac uptake could benefit from disease-modifying treatment, according to a new study.

• Case report looks at possible link between ATTR-CM and rheumatoid arthritis

  Researchers looked at a patient with rheumatoid arthritis who developed transthyretin amyloid cardiomyopathy-mediated heart failure.

• Study identifies variables associated with early death in patients with ATTR-CM

  Researchers identified factors that can accurately predict patients with wild-type ATTR-CM who are at high risk of early death.

• ATTR-CM amyloid fibers had the same structure in all organs of a patient

  Researchers found no significant difference in the structure of amyloid fibrils accumulated in different organs in a patient with ATTR-CM.